Stress Reduction Prolongs Life in Women With Coronary Disease
Key result
A group-based psychosocial intervention program significantly reduced mortality compared to usual care in women with coronary heart disease (7% vs 20%; OR 0.33; 95% CI 0.15-0.74; P=0.007).
Why the study?
Does a group-based psychosocial intervention program reduce mortality in women hospitalized for coronary heart disease?
Population
n=237 consecutive women patients, aged 75 years or younger, hospitalized for acute myocardial infarction…
Comparison
Group-based psychosocial intervention program… vs Usual care.
Design
RCT, Randomized
Follow-up
mean 7.1 years
Authors
Discussion
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Implication
Supports integrating group psychosocial intervention into care for women with CHD; extends randomized evidence for mortality reduction.
Key Points
- This study aims to evaluate the impact of a stress reduction program on the survival of women with coronary heart disease.
- Randomized 237 women hospitalized for coronary events to intervention or usual care groups.
- Implemented a year-long group-based psychosocial intervention focusing on stress management and education.
- Followed up for a mean duration of 7.1 years after randomization.
- 20% of women in usual care died compared to 7% in the stress reduction group, indicating a protective effect (odds ratio 0.33; 95% CI 0.15 to 0.74; P=0.007).
- Inclusion of clinical prognostic factors in models confirmed these results (P=0.009).
- The program appears to prolong life independently of other health factors.
Study Design
Type
RCT (n=237)
Structured PICO
Does a group-based psychosocial intervention program reduce mortality in women hospitalized for coronary heart disease?
P
Population
237 women aged ≤75 years hospitalized for acute myocardial infarction, CABG, or PCI, followed for a mean of 7.1 years.
I
Intervention
Group-based psychosocial intervention program (groups of 4 to 8 women meeting for 20 sessions over a year, initiated 4 months after hospitalization) including education, relaxation training, self-monitoring, and cognitive restructuring.
C
Comparator
Usual care.
O
Outcome
All-cause mortality (death) at mean 7.1 years follow-up.hard clinical
Main Result
Odds Ratio: 0.33 (95% CI 0.15–0.74)
Absolute Event Rate: 7% vs 20%
p-value: p=0.007
A group-based psychosocial stress reduction program significantly reduced long-term mortality in women with coronary heart disease compared to usual care.
Limitations
- Mechanisms remain unclear
Cite This Study
Orth‐Gomér et al. (2009) conducted an RCT in Coronary heart disease (n=237). Group-based psychosocial intervention program vs. Usual care was evaluated on Death (OR 0.33, 95% CI 0.15 to 0.74, p=0.007). A group-based psychosocial intervention program significantly reduced mortality compared to usual care in women with coronary heart disease (7% vs 20%; OR 0.33; 95% CI 0.15-0.74; P=0.007).