Key result
Artificially created cul-de-sac after Amulet LAAO leads to late device-related thrombus.
Why the study?
Device-related thrombus occurs in 3-4% of patients following left atrial appendage occlusion, prompting examination of its causes and mitigation techniques.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
Incomplete sealing and failure to meet the 'CLOSE' criteria during LAAO device implantation can create an artificial cul-de-sac leading to significant device-related thrombus.
Left Atrial Appendage Occlusion (LAAO) is an alternative to lifelong anticoagulation in patients with atrial fibrillation.1,2 Device related thrombus (DRT) occurs in 3-4% of patients following LAAO.3-5 We describe a case of a large, unique morphology DRT and review the likely cause and procedural techniques to mitigate this.
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Kalaba et al. (2024) conducted a case report in Atrial fibrillation (n=1). Left atrial appendage occlusion (Amulet device) was evaluated on Device-related thrombus. An 85-year-old male developed a large device-related thrombus 6 months post-left atrial appendage occlusion with the Amulet device, attributed to an artificially created cul-de-sac.
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