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January 1, 2014Clinical Medicine Insights CardiologyOpen Access

Left Atrial Appendage Closure Devices

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Key result

This article reviews the different techniques and devices for left atrial appendage occlusion as an alternative to oral anticoagulation for stroke prevention in atrial fibrillation.

Why the study?

Do left atrial appendage closure devices provide an effective and safe alternative to oral anticoagulation for stroke prevention in patients with atrial fibrillation?

Population

Patients with atrial fibrillation (AF)

Comparison

Left atrial appendage occlusion techniques and… vs Oral anticoagulation

Design

Review

Authors

JRJorge RomeroIPIrving E. PerezAKAndrew Krumerman

Discussion

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Member takes

Overview

May inform device selection for anticoagulation-intolerant AF patients; leaves open head-to-head trials versus contemporary NOACs.

Structured PICO

Do left atrial appendage closure devices provide an effective and safe alternative to oral anticoagulation for stroke prevention in patients with atrial fibrillation?

P
Population
Patients with atrial fibrillation (AF)
I
Intervention
Left atrial appendage (LAA) occlusion techniques and devices
C
Comparator
Oral anticoagulation (warfarin and novel anticoagulants)
O
Outcome
Efficacy and safety of LAA occlusion devices

Left atrial appendage occlusion serves as an alternative therapeutic approach to oral anticoagulation for stroke prevention in patients with atrial fibrillation.

Cite This Study

Romero et al. (2014) conducted a review in Atrial fibrillation. Left atrial appendage closure devices vs. Oral anticoagulation was evaluated. This article reviews the different techniques and devices for left atrial appendage occlusion as an alternative to oral anticoagulation for stroke prevention in atrial fibrillation.

synapsesocial.com/papers/6a9a7da38fdb2eaad045ca14https://doi.org/10.4137/cmc.s14043
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Atrial Appendage Exclusion for Stroke Prevention in Atrial Fibrillation2012 · 16 citations
  2. 2Percutaneous Left Atrial Appendage Transcatheter Occlusion to Prevent Stroke in High-Risk Patients With Atrial Fibrillation2002 · 435 citations
  3. 3Success of Surgical Left Atrial Appendage Closure2008 · 554 citations
  4. 4Anatomy of the Normal Left Atrial Appendage1997 · 420 citations
  5. 5Apixaban versus Warfarin in Patients with Atrial Fibrillation2011 · 8,999 citations