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January 1, 2011Arrhythmia & Electrophysiology ReviewOpen Access

Left Atrial Appendage Closure Devices For Stroke Prevention

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Key result

This article reviews current endovascular and epicardial catheter-based left atrial appendage occlusion devices and the clinical data supporting their use for stroke prevention in atrial fibrillation.

Why the study?

Does endovascular and epicardial catheter-based left atrial appendage (LAA) occlusion devices prevent stroke in patients with atrial fibrillation?

Population

Patients with atrial fibrillation

Comparison

Endovascular and epicardial catheter-based left… vs Systemic anticoagulation

Design

Review

Authors

SKSunil KapurMMMoussa Mansour

Discussion

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Overview

LAA occlusion devices may serve as anticoagulation alternatives in select AF patients; leaves open need for additional randomized efficacy data.

Structured PICO

Does endovascular and epicardial catheter-based left atrial appendage (LAA) occlusion devices prevent stroke in patients with atrial fibrillation?

P
Population
Patients with atrial fibrillation
I
Intervention
Endovascular and epicardial catheter-based left atrial appendage (LAA) occlusion devices
C
Comparator
Systemic anticoagulation
O
Outcome
Stroke prevention

Catheter-based left atrial appendage occlusion devices are reviewed as an emerging alternative to systemic anticoagulation for stroke prevention in patients with atrial fibrillation.

Cite This Study

Kapur et al. (2011) conducted a review in Atrial fibrillation. Left atrial appendage (LAA) occlusion devices was evaluated. This article reviews current endovascular and epicardial catheter-based left atrial appendage occlusion devices and the clinical data supporting their use for stroke prevention in atrial fibrillation.

synapsesocial.com/papers/6a7b60eee357fbdac589d950https://doi.org/10.15420/articles/left-atrial-appendage-closure-devices-stroke-prevention
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous closure of left atrial appendage to prevent embolic events in high‐risk patients with chronic atrial fibrillation2009 · 44 citations
  2. 2Left atrial appendage closure with Amplatzer cardiac plug for stroke prevention in atrial fibrillation: Initial Asia‐Pacific experience2011 · 163 citations
  3. 3Left atrial appendage: structure, function, and role in thromboembolism1999 · 693 citations
  4. 4Transcatheter left atrial appendage occlusion with Amplatzer devices to obviate anticoagulation in patients with atrial fibrillation2003 · 219 citations
  5. 5Occluding the left atrial appendage: anatomical considerations2007 · 169 citations