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January 1, 2011Cardiology Research and PracticeOpen Access

Left Atrial Appendage Closure in Atrial Fibrillation: A World without Anticoagulation?

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Key result

Percutaneous left atrial appendage occlusion devices are reviewed for their feasibility and efficacy in preventing stroke among patients with nonvalvular atrial fibrillation.

Why the study?

Do percutaneous left atrial appendage occlusion devices prevent stroke in patients with nonvalvular atrial fibrillation?

Population

Patients with nonvalvular atrial fibrillation

Design

Review

Authors

TCTahmeed ContractorAKAtul Khasnis

Discussion

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Overview

May inform device discussions in nonvalvular AF; leaves open definitive efficacy conclusions pending higher-level evidence.

Structured PICO

Do percutaneous left atrial appendage occlusion devices prevent stroke in patients with nonvalvular atrial fibrillation?

P
Population
Patients with nonvalvular atrial fibrillation
I
Intervention
Percutaneous left atrial appendage (LAA) occlusion devices
O
Outcome
Stroke prevention

This review summarizes the rationale, feasibility, and efficacy of percutaneous left atrial appendage occlusion devices for stroke prevention in patients with nonvalvular atrial fibrillation.

Cite This Study

Contractor et al. (2011) conducted a review in Atrial Fibrillation. Percutaneous left atrial appendage occlusion was evaluated. Percutaneous left atrial appendage occlusion devices are reviewed for their feasibility and efficacy in preventing stroke among patients with nonvalvular atrial fibrillation.

synapsesocial.com/papers/6a208f66a698ff314ccc41efhttps://doi.org/10.4061/2011/752808
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Atrial Appendage Occlusion Does Not Eliminate the Need for Warfarin2009 · 65 citations
  2. 2Transcatheter left atrial appendage occlusion with Amplatzer devices to obviate anticoagulation in patients with atrial fibrillation2003 · 219 citations
  3. 3Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation2007 · 4,828 citations
  4. 4Warfarin in atrial fibrillation: underused in the elderly, often inappropriately used in the young1999 · 31 citations
  5. 5Epidemiologic assessment of chronic atrial fibrillation and risk of stroke1978 · 1,549 citations