Vitamin K Deficiency: Pathophysiology, Clinical Manifestations, Diagnosis and Management — A Narrative Review

Key Result

Universal neonatal prophylaxis with intramuscular phytonadione remains the most effective public health measure for preventing morbidity and mortality associated with vitamin K deficiency bleeding.

Key Points

• To evaluate the pathophysiology, clinical manifestations, diagnosis, and management strategies for vitamin K deficiency.
• Narrative review analyzing existing literature on vitamin K deficiency mechanisms and outcomes.
• Assessment of clinical signs associated with vitamin K deficiency.
• Evaluation of current diagnostic and management strategies.
• Describes various clinical manifestations including coagulopathy due to vitamin K deficiency.
• Outlines effective management strategies, including supplementation and dietary adjustments.