Key result
PEEP in ARDS can induce systemic venous congestion and organ dysfunction despite improved oxygenation.
Reframes PEEP titration in ARDS as a systemic hemodynamic decision rather than purely a respiratory adjustment, highlighting the underappreciated risk of venous congestion and organ dysfunction.
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May warrant cautious PEEP titration in ARDS to limit venous congestion; leaves open optimal balancing strategies for prospective trials.
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Benites et al. (2026) conducted a review in Acute respiratory distress syndrome (ARDS). Positive end-expiratory pressure (PEEP) was evaluated. Positive end-expiratory pressure in ARDS can induce systemic venous congestion and organ dysfunction despite improved oxygenation, requiring a balance between lung mechanics and venous return.
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