Key result
Chinese herbal medicines and active ingredients modulate regulatory pathways to reduce pyroptosis markers.
Leaves open a role for herbal agents targeting pyroptosis in diabetic cardiomyopathy; larger RCTs needed before clinical consideration.
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Fu et al. (2026) conducted a review in Diabetic Cardiomyopathy. Chinese Herbal Medicine and Active Ingredients (Quercetin, Puerarin, Curcumin, Arbutin, Berberine, FTZ, Shengmai Yin) was evaluated on Pyroptosis outcomes and regulatory pathways. Chinese herbal medicines and active ingredients, such as quercetin, puerarin, and curcumin, modulate regulatory pathways to reduce pyroptosis markers like NLRP3, caspase-1, and GSDMD.
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