Why the study?
Does a TAVI-first strategy compared to an RA-first strategy improve 1-year MACE in older patients with severe AS and calcified CAD requiring both TAVI and RA-assisted PCI?
Observational (n=64)
Yes
Does a TAVI-first strategy compared to an RA-first strategy improve 1-year MACE in older patients with severe AS and calcified CAD requiring both TAVI and RA-assisted PCI?
Absolute Event Rate: 11.8% vs 10%
p-value: p=1.00
In patients with severe aortic stenosis and calcified coronary artery disease, both TAVI-first and RA-first staged strategies appear feasible and are associated with comparable 1-year clinical outcomes.
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Madhavan et al. (2026) conducted an observational in Severe aortic stenosis and calcified coronary artery disease (n=64). TAVI-first strategy vs. Rotational atherectomy (RA)-first strategy was evaluated on Major adverse cardiac events (MACE), defined as the composite of all-cause death and rehospitalization at 1 year (p=1.00).
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