Key result
Bridging BAV rapidly stabilizes acute valve syndrome, but evidence vs emergent TAVR remains inconclusive.
Why the study?
Does balloon aortic valvuloplasty as a bridge therapy improve outcomes compared to emergent TAVR in patients with acute valve syndrome?
Does balloon aortic valvuloplasty as a bridge therapy improve outcomes compared to emergent TAVR in patients with acute valve syndrome?
Balloon aortic valvuloplasty may serve as a viable bridge to TAVR in hemodynamically unstable patients with acute valve syndrome, though current evidence is limited by confounding and small sample sizes.
Acute valve syndrome represents a high-acuity, decompensated presentation of severe aortic stenosis (AS), often manifesting as acute heart failure, cardiogenic shock, or cardiac arrest. Transcatheter aortic valve replacement (TAVR) remains the only durable therapy for severe AS in patients with prohibitive surgical risk, yet acute valve syndrome patients may be too unstable for standard preprocedural planning. Balloon aortic valvuloplasty (BAV) has re-emerged as a bridge strategy that can provide rapid hemodynamic stabilization and permit subsequent valve replacement. Registry analyses report lower mortality in emergent TAVR compared with BAV, but these comparisons are confounded by procedural indication and unmatched AS severity. Smaller hemodynamically characterized cohorts suggest that selected patients who stabilize after BAV and proceed to TAVR may achieve outcomes comparable to direct TAVR, although these studies remain underpowered for definitive inference. In this narrative review, we evaluate evidence comparing BAV-bridged strategies with emergent TAVR, identify key evidence gaps, and discuss how acute hemodynamic status may inform Heart Team decision-making.
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Saleh et al. (2026) conducted a review in Acute valve syndrome (severe aortic stenosis). Balloon aortic valvuloplasty (BAV) vs. Emergent TAVR was evaluated. Balloon aortic valvuloplasty as a bridge to TAVR in acute valve syndrome provides rapid stabilization, but current evidence comparing it to emergent TAVR remains confounded and underpowered.
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