82686 | Effect of a Horizontal Aorta on Procedural and Clinical Outcomes in Contemporary Transcatheter Aortic Valve Replacement

Massimo Baudo; Serge Sicouri; Dimitrios Magouliotis; Scott Goldman; Khalid Ridwan; Eric Gnall; William Gray; Basel Ramlawi

doi:10.1016/j.shj.2026.100900

June 1, 2026Structural HeartOpen Access

82686 | Effect of a Horizontal Aorta on Procedural and Clinical Outcomes in Contemporary Transcatheter Aortic Valve Replacement

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Key result

Horizontal aorta shows unclear effects on procedural and clinical outcomes during TAVR.

Why the study?

Does a horizontal aorta (>48°) influence procedural and clinical outcomes in patients undergoing TAVR?

Key Points

To evaluate the impact of a horizontal aorta on procedural performance and clinical outcomes in patients undergoing transcatheter aortic valve replacement with balloon-expandable versus self-expanding valves.
Comparative cohort analysis of patients receiving transcatheter aortic valve replacement (TAVR) with contemporary balloon-expandable (BEV) or self-expanding valves (SEV).
Patients were categorized and evaluated based on aortic anatomy, defining a horizontal aorta as an angle greater than 48 degrees.
Procedural performance metrics were evaluated in relation to severe aortic root angulation across contemporary valve platforms.
Clinical outcomes were tracked to establish device-specific procedural efficacy in sharply angulated aortic anatomies.

Structured PICO

Does a horizontal aorta (>48°) influence procedural and clinical outcomes in patients undergoing TAVR?

P

Population

Patients treated with contemporary balloon-expandable (BEV) and self-expanding valves (SEV) for transcatheter aortic valve replacement (TAVR)

I

Intervention

Transcatheter aortic valve replacement (TAVR) in the presence of a horizontal aorta (>48°)

C

Comparator

Transcatheter aortic valve replacement (TAVR) without a horizontal aorta

O

Outcome

Procedural and clinical outcomes

Abstract

Evidence remains inconclusive as to whether a horizontal aorta influences procedural performance with the use of balloon-expandable (BEV) or self-expanding valves (SEV). This study compared outcomes in patients with and without a horizontal aorta (>48°) treated with contemporary BEV and SEV for transcatheter aortic valve replacement (TAVR).

Discussion

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Cite This Study

Baudo et al. (2026) studied this question.

synapsesocial.com/papers/6a3c2381d15afadd906fa417 https://doi.org/10.1016/j.shj.2026.100900

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82686 | Effect of a Horizontal Aorta on Procedural and Clinical Outcomes in Contemporary Transcatheter Aortic Valve Replacement

Key Points

Structured PICO

Abstract

Discussion

Cite This Study

82686 | Effect of a Horizontal Aorta on Procedural and Clinical Outcomes in Contemporary Transcatheter Aortic Valve Replacement

Key Points

Structured PICO

Abstract

Discussion

Cite This Study

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