Key result
Maternal anti-Ro/SSA antibodies linked to adverse outcomes from fetal atrial flutter with complete AV block.
Why the study?
Atrial arrhythmias are rarely reported in patients with maternal anti-Ro/SSA autoantibodies.
Case Report (n=1)
This case highlights a rare presentation of fetal atrial flutter superimposed on immune-mediated complete AV block due to maternal anti-Ro/SSA antibodies.
Clinicians should monitor anti-Ro/SSA-exposed fetuses for atrial arrhythmias; case report leaves open incidence and management.
Fetal exposure to maternal anti-Ro/SSA antibodies can result in several cardiac disorders, most commonly atrioventricular block (AVB). Immune-mediated complete AVB is typically an irreversible complication of maternal anti-Ro antibodies and could result in intrauterine fetal demise. Atrial arrhythmias are rarely reported in patients with maternal anti-Ro/SSA autoantibodies. This report presents a rare combination of fetal arrhythmias, with transient episodes of fetal atrial flutter superimposed on a complete AVB rhythm. No antiarrhythmic medication was required. However, the adverse outcome associated with advanced AVB was unavoidable.
No takes yet. Share an insight, caveat, or question.
Rakha et al. (2026) conducted a case report in Fetal atrial flutter and immune-mediated complete atrioventricular block (n=1). Maternal anti-Ro/SSA antibodies was evaluated on Fetal arrhythmias and clinical outcome. Fetal exposure to maternal anti-Ro/SSA antibodies resulted in a rare combination of transient fetal atrial flutter superimposed on complete atrioventricular block, leading to an adverse outcome.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: