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June 25, 2020Journal of Atherosclerosis and ThrombosisOpen Access

New Horizons of Arterial Stiffness Developed Using Cardio-Ankle Vascular Index (CAVI)

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Key result

Cardio-ankle vascular index (CAVI) is a blood pressure-independent marker of arterial stiffness, with a proposed cut-off value of 9 for predicting future cardiovascular disease events.

Why the study?

To summarize recently accumulated evidence on the cardio-ankle vascular index (CAVI), focusing on proposed cut-off values for cardiovascular events and its role as a vascular function index.

Design

Review

Authors

ASAtsuhito SaikiMOMasahiro OhiraTYTakashi Yamaguchi

Discussion

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Overview

Supports CAVI for BP-independent arterial stiffness assessment; extends observational evidence but leaves open prospective outcome trials.

Key Points

  • The aim is to review evidence of CAVI as a predictor of cardiovascular disease and its independence from blood pressure.
  • Summarized clinical evidence regarding CAVI and cardiovascular events.
  • Discussed optimal cut-off values for predicting CVD.
  • Reviewed recent findings on CAVI's relationship with various health conditions.
  • CAVI is elevated in patients with coronary artery disease and chronic kidney disease.
  • CAVI of 9 is proposed as the optimal cut-off value for predicting CVD.
  • CAVI demonstrates acute changes under mental stress and other pathophysiological conditions.

Structured PICO

P
Population
Patients with various atherosclerotic diseases, coronary risk factors, and healthy individuals assessed for arterial stiffness.
E
Exposure
Cardio-Ankle Vascular Index (CAVI) measurement

CAVI is a useful, blood pressure-independent marker of arterial stiffness, with proposed cut-off values of 8.0 for subclinical atherosclerosis and 9.0 for predicting cardiovascular events.

Cite This Study

Saiki et al. (2020) conducted a review in Arterial stiffness and cardiovascular diseases. Cardio-Ankle Vascular Index (CAVI) was evaluated. Cardio-ankle vascular index (CAVI) is a blood pressure-independent marker of arterial stiffness, with a proposed cut-off value of 9 for predicting future cardiovascular disease events.

synapsesocial.com/papers/6a3dc306e67a1dc2fe0aee75https://doi.org/10.5551/jat.rv17043
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of Arterial Stiffness Using the Cardio-Ankle Vascular Index – What We Know and What We Strive for2021 · 9 citations
  2. 2Evaluation of Arteriosclerotic Vascular Disease with a New Noble Stiffness Indicator, Cardio-Ankle Vascular Index (CAVI)2012 · 3 citations
  3. 3Cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness2013 · 141 citations
  4. 4Arterial stiffness in health and disease: The role of cardio–ankle vascular index2021 · 91 citations
  5. 5Assessment of Arterial Stiffness Using the Cardio-Ankle Vascular Index2016 · 65 citations