Why the study?
In the ED, thorough cardiovascular evaluation cannot be accomplished by physical examination alone, prompting evaluation of EPSS via POCUS to diagnose reduced LVEF.
Does E-Point Septal Separation (EPSS) measured by POCUS accurately diagnose reduced LVEF in ED patients with chest pain or dyspnea?
Comparison
POCUS EPSS measurement vs transthoracic echocardiogram
Design
Retrospective analysis of a convenience sample
Key result
E-Point Septal Separation measured via POCUS accurately diagnosed reduced left ventricular ejection fraction (≤40%) in emergency department patients, demonstrating an AUC-ROC of 0.91.
Authors
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EPSS at 9.5 mm may aid bedside LVEF assessment in ED; leaves open prospective validation before clinical adoption.
Observational (n=96)
Blinded (index and reference tests)
No
Does E-Point Septal Separation (EPSS) measured by POCUS accurately diagnose reduced LVEF in ED patients with chest pain or dyspnea?
Effect estimate: AUC-ROC 0.91 (95% CI 0.85-0.97)
EPSS measured by POCUS is a highly accurate tool for diagnosing reduced LVEF in emergency department patients presenting with cardiovascular symptoms.
Núñez-Ramos et al. (2022) conducted an observational in Chest pain or dyspnea with suspected left ventricular dysfunction (n=96). E-Point Septal Separation (EPSS) via Point-of-Care Ultrasound vs. Transthoracic Echocardiogram (TTE) LVEF calculation was evaluated on Diagnostic accuracy (AUC-ROC) of EPSS to predict reduced Ejection Fraction (LVEF ≤40%) (AUC-ROC 0.91, 95% CI 0.85-0.97). E-Point Septal Separation measured via POCUS accurately diagnosed reduced left ventricular ejection fraction (≤40%) in emergency department patients, demonstrating an AUC-ROC of 0.91.