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June 27, 2026Nursing and Health Sciences

Understanding the Predictors of Self‐Perceived Burden in Patients With Liver Cancer

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Why the study?

Treatment complexity and severe side effects of liver cancer impair quality of life and lead to self-perceived burden, prompting the need to identify its predictors.

What are the predictors of self-perceived burden in patients with liver cancer?

Population

139 patients with liver cancer

Design

Cross-sectional study

Key result

Unemployment before illness, chemotherapy, and confrontation or fantasy coping strategies were significant predictors of self-perceived burden, which was experienced by 97.82% of liver cancer patients.

Authors

BLBingyang LiuDCDongmei ChuKSKim Lam Soh

Discussion

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Overview

High SPB prevalence may warrant clinical screening in liver cancer; leaves open whether targeting predictors improves outcomes.

Key Points

  • This study explores factors that contribute to self-perceived burden (SPB) in patients with liver cancer.
  • Cross-sectional design involving 139 liver cancer patients.
  • Used multiple linear regression to analyze predictors of SPB.
  • Examined variables such as unemployment, chemotherapy, and coping strategies.
  • 97.82% of participants reported experiencing SPB, with an average score of 63.58 ± 15.33.
  • Unemployment before illness and chemotherapy significantly predicted higher SPB.
  • Confrontation and fantasy coping strategies were linked to increased SPB.

Study Design

Type

Cross-Sectional (n=139)

Structured PICO

What are the predictors of self-perceived burden in patients with liver cancer?

P
Population
139 patients with liver cancer assessed for predictors of self-perceived burden.
O
Outcome
Predictors of self-perceived burden (SPB)patient reported

The vast majority of liver cancer patients experience self-perceived burden, which is significantly predicted by unemployment, chemotherapy, and specific coping strategies, highlighting the need for targeted interventions.

Cite This Study

Liu et al. (2026) conducted a cross-sectional in Liver cancer (n=139). Unemployment, chemotherapy, and confrontation/fantasy coping strategies was evaluated on Self-perceived burden (SPB). Unemployment before illness, chemotherapy, and confrontation or fantasy coping strategies were significant predictors of self-perceived burden, which was experienced by 97.82% of liver cancer patients.

synapsesocial.com/papers/6a3f68a3aea7db3c1953fa21https://doi.org/10.1111/nhs.70378
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