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June 27, 2026Drugs - Real World OutcomesOpen Access

Assessment of Potential Drug–Drug Interactions and Associated Factors Among Pulmonary Inpatients in a Tertiary Care Hospital: A Cross-Sectional Study

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Authors

NDNim Bahadur DangiHSHari Prasad SapkotaGKGobinda Kandel

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Overview

Cross-sectional study identifies prevalence of drug-drug interactions in pulmonary inpatients, indicating the need for careful medication management.

Key Points

  • This study aims to determine the prevalence of potential drug-drug interactions (pDDIs) and their associated risk factors among hospitalized pulmonary patients.
  • Cross-sectional study conducted from July 2024 to December 2025 among pulmonary patients in a tertiary care hospital in Nepal.
  • Included patients with a hospital stay of ≥ 24 hours receiving two or more medications.
  • pDDIs identified using Lexicomp and IBM Micromedex, with data analyzed using SPSS V16.
  • 36.1% of patients had pDDIs identified by Lexicomp; 19.9% by Micromedex.
  • Most interactions classified as major severity: 66.18% by Lexicomp and 53.33% by Micromedex.
  • Factors significantly associated with increased risk of pDDIs included polypharmacy, longer hospital stays, co-morbidities, alcohol consumption, and advanced age.

Cite This Study

Dangi et al. (2026) studied this question.

synapsesocial.com/papers/6a3f68cdaea7db3c1953fcaahttps://doi.org/10.1007/s40801-026-00563-9
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