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June 27, 2026DiagnosticsOpen Access

Early Inflammatory Biomarkers, Ventricular Dysfunction and In-Hospital Mortality in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

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Authors

DMDan Claudiu MăgureanuIuliu Hațieganu University of Medicine and PharmacyMHMaria Luiza HiceagAssociation of Indian UniversitiesCRCamelia Bianca RusUniversity of Oradea

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Overview

Retrospective study evaluates in-hospital mortality in STEMI patients, linking inflammation to ventricular dysfunction.

Key Points

  • This study evaluates the link between inflammatory biomarkers, echocardiographic markers of ventricular dysfunction, and in-hospital mortality in STEMI patients after PCI.
  • Retrospective observational study of 600 patients with STEMI treated with primary PCI.
  • Measured inflammatory biomarkers included CRP, NLR, PLR, SII, and CLR upon admission.
  • Used multivariable logistic regression to identify predictors of in-hospital mortality.
  • In-hospital mortality was observed in 54 patients (9.0%).
  • Higher CRP and CLR levels were found in patients with LVEF ≤ 40% (p < 0.01).
  • Age, LVEF < 40%, and the number of residual coronary lesions were independent predictors of mortality.

Cite This Study

Măgureanu et al. (2026) studied this question.

synapsesocial.com/papers/6a3f68f5aea7db3c1953fda5https://doi.org/10.3390/diagnostics16131978
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical and laboratory predictors of early mortality in patients with acute myocardial infarction treated with primary percutaneous coronary intervention2016
  2. 2Relation of inflammatory markers with myocardial and microvascular injury in patients with reperfused ST-elevation myocardial infarction2016 · 86 citations
  3. 3Association of inflammatory markers based on routine blood with prognosis in patients underwent percutaneous coronary intervention2024 · 5 citations
  4. 4Prognostic factors of in-hospital mortality in all comers with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention2016 · 11 citations
  5. 5Early Predictors of In-Hospital Mortality and Cardiac Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Early Revascularization2026