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This study aims to analyze the clinical and economic burden of influenza and influenza-like illness in Germany from 2019 to 2025.

Clinical and Economic Inpatient Burden of Influenza and Influenza-Like Illness in Germany 2019–2025: Analysis of Nationwide Hospital Data

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This study aims to analyze the clinical and economic burden of influenza and influenza-like illness in Germany from 2019 to 2025.
Conducted a descriptive, retrospective analysis of nationwide hospital data from the German Institute for Hospital Reimbursement.
Identified influenza/ILI hospitalizations using ICD-10 codes J09-J11 recorded as primary diagnosis.
Assessed outcomes including hospitalization counts, incidence rates, mean length of stay, ICU admissions, in-hospital mortality, and costs.
Identified 240,646 influenza/ILI hospitalizations, with the highest burden (87,745 cases) in the 2024-2025 season.
Adults aged ≥ 60 years accounted for 48% of hospitalizations and 92% of 10,054 in-hospital deaths.
Estimated total inpatient costs of influenza/ILI were highest in 2024-2025 at €390 million.

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Descriptive analysis reports hospitalization trends and economic impacts of influenza in Germany, highlighting older adults' risks.

Meyer et al. (2026) studied this question.

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