What question did this study set out to answer?

To highlight the re-emergence of thoracic actinomycosis and its clinical relevance in the context of non-resolving pulmonary infiltrates.

June 27, 2026Lung IndiaOpen Access

Thoracic actinomycosis in the 21st century – A re-emerging infection: A case series from India

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Case series describes thoracic actinomycosis and its management in a high tuberculosis region, indicating its re-emergence.

To highlight the re-emergence of thoracic actinomycosis and its clinical relevance in the context of non-resolving pulmonary infiltrates.
Retrospective analysis of four patients diagnosed with thoracic actinomycosis.
Evaluation of clinical presentations, radiological findings, diagnostic methods, and treatment outcomes.
Utilization of bronchoscopic biopsy, CT-guided biopsy, surgical excision, and sputum examination for diagnosis.
Patients showed nonspecific respiratory symptoms and non-resolving pulmonary infiltrates, mimicking tuberculosis.
Definitive diagnosis involved identifying sulphur granules and branching filamentous organisms.
All patients treated with penicillin showed favorable clinical outcomes and radiological resolution, with no reported mortality.

Spurthi et al. (2026) studied this question.

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