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June 25, 2026Pediatric RadiologyOpen Access

Pediatric SARS-CoV-2 long term outcomes study: chest radiographic and computed tomography findings at baseline

Jonathan Zember Evrim B. Turkbey Eric Chu Allyson Mateja C Jason Liang Karyl Barron Gadwyn Sánchez Roberta L. DeBiasi Meagan E. Williams Dorothy Bulas

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Key Points

This study aims to evaluate long-term radiologic findings in pediatric patients who recovered from SARS-CoV-2 infection compared to uninfected controls.
Longitudinal cohort study involving 846 children, including 700 infected and 146 uninfected, evaluated at 9.8 months post-infection.
Participants underwent chest radiographic (CXR) and low-dose chest computed tomography (CT) examinations.
Comparative analysis used generalized estimating equations with cohorts (infected vs. uninfected) as a predictor.
The prevalence of radiologic abnormalities was 32.1% in infected children compared to 24.0% in controls (P=0.016).
CXR abnormalities were significantly higher in infected children (21.2%) than uninfected (12.4%; OR 2.44; 95% CI 1.19-5.02).
No statistically significant difference in CT abnormalities between groups (46.2% vs. 42.1%; P=0.46) and no correlation with pulmonary symptoms.

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Implication

Longitudinal cohort study compares chest imaging in SARS-CoV-2 infected children and controls, revealing key insights.

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Cite This Study

Zember et al. (2026) studied this question.

synapsesocial.com/papers/6a3f69a5aea7db3c195405a0 https://doi.org/10.1007/s00247-026-06701-3

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