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Explore the structural and functional diversity of haptoglobin and its potential as a disease biomarker.

Haptoglobin as a Biomarker

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Review discusses the potential of haptoglobin as a biomarker for various diseases, indicating its importance in clinical practice.

Explore the structural and functional diversity of haptoglobin and its potential as a disease biomarker.
Review of literature on haptoglobin's biophysical characteristics, genotypes, and post-translational modifications.
Examination of haptoglobin's role in pathology and its association with various diseases.
Haptoglobin can exist in multiple proteoforms, suggesting different functions in pathological processes.
Phenotypic variation in haptoglobin indicates individual predisposition to diseases, including malignant neoplasms.
Glycosylation of the β-chain of haptoglobin is a key post-translational modification affecting its structure and function.

Naryzny et al. (2021) studied this question.

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