Key result
No clinical data is present in the provided text, which consists only of the journal's editorial board and publication information.
Why the study?
Total primary knee replacement causes significant bleeding and frequent transfusions, prompting the search for safe, low-cost oral antifibrinolytics such as aminocaproic acid compared to tranexamic acid.
Does oral aminocaproic acid reduce postoperative bleeding similarly to oral tranexamic acid in patients undergoing total primary knee replacement?
Population
92 patients undergoing total primary knee replacement
Comparison
Oral aminocaproic acid vs oral tranexamic acid
Design
Randomized clinical trial
Authors
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Oral aminocaproic acid matches oral tranexamic acid for bleeding control after TKA; extends low-cost antifibrinolytic options for practice and trials.
Does oral aminocaproic acid reduce postoperative bleeding similarly to oral tranexamic acid in patients undergoing total primary knee replacement?
Oral aminocaproic acid is similarly effective to oral tranexamic acid for reducing postoperative bleeding in total knee arthroplasty, with potentially fewer adverse events.
Morales-Ávalos et al. (2019) studied this question. No clinical data is present in the provided text, which consists only of the journal's editorial board and publication information.
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