Eradication of a Multidrug-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Isolate Following Oral and Intra-rectal Therapy With a Custom Made, Lytic Bacteriophage Preparation

Mario Corbellino; Nicolas Kieffer; Mzia Kutateladze; Nana Balarjishvili; Lika Leshkasheli; Lia Askilashvili; George Tsertsvadze; Sara Giordana Rimoldi; Deia Nizharadze; Naomi Hoyle; Lia Nadareishvili; Spinello Antinori; Cristina Pagani; D. Scorza; Ai Ling Romanò; Sandro Ardizzone; Piergiorgio Danelli; Maria Rita Gismondo; Massimo Galli; Patrice Nordmann; Laurent Poirel

doi:10.1093/cid/ciz782

Abstract

In July 2017, a patient presented colonization with a multidrug-resistant, carbapenemase (KPC-3)-producing Klebsiella pneumoniae isolate. A custom-made, lytic bacteriophage preparation was administered to the patient in December 2017, with subsequent eradication of the microorganism and without adverse effects.

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Corbellino et al. (2019) studied this question.

synapsesocial.com/papers/6a3fde3f4a2d33c351cd478f https://doi.org/10.1093/cid/ciz782

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Eradication of a Multidrug-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Isolate Following Oral and Intra-rectal Therapy With a Custom Made, Lytic Bacteriophage Preparation

Abstract

Discussion

Cite This Study

Eradication of a Multidrug-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Isolate Following Oral and Intra-rectal Therapy With a Custom Made, Lytic Bacteriophage Preparation

Abstract

Discussion

Cite This Study

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