Why the study?
Does COPD increase the risk of incident atrial fibrillation in a population-based cohort?
Population
10,943 subjects from a population-based cohort (Rotterdam Study)
Comparison
Chronic obstructive pulmonary disease (COPD) vs Subjects without COPD
Design
Cohort
Follow-up
long-term
Key result
COPD was associated with a 28% increased risk of incident atrial fibrillation compared to subjects without COPD (HR 1.28; 95% CI 1.04-1.57).
Authors
Loading...
COPD-associated AF risk elevation may warrant clinical vigilance; leaves open whether targeted interventions improve outcomes.
Cohort (n=10,943)
Does COPD increase the risk of incident atrial fibrillation in a population-based cohort?
Hazard Ratio: 1.28 (95% CI 1.04–1.57)
Absolute Event Rate: 14% vs 8%
COPD is an independent risk factor for incident atrial fibrillation, with the risk further elevated by frequent exacerbations, enlarged left atrium, and systemic inflammation.
Grymonprez et al. (2018) conducted a cohort in Chronic obstructive pulmonary disease and atrial fibrillation (n=10,943). Chronic obstructive pulmonary disease (COPD) vs. Subjects without COPD was evaluated on Incident atrial fibrillation (HR 1.28, 95% CI 1.04-1.57). COPD was associated with a 28% increased risk of incident atrial fibrillation compared to subjects without COPD (HR 1.28; 95% CI 1.04-1.57).