Key result
Serum uric acid (OR 1.004), platelet count, hematocrit, and concomitant P2Y12 receptor inhibitor use (OR 1.965) were independently correlated with high on-aspirin platelet reactivity.
Why the study?
What are the independent predictors of high on-aspirin platelet reactivity in elderly patients with coronary artery disease?
Observational (n=275)
What are the independent predictors of high on-aspirin platelet reactivity in elderly patients with coronary artery disease?
Odds Ratio: 1.004 (95% CI 1–1.007)
p-value: p=0.048
Serum uric acid, platelet count, hematocrit, and concomitant P2Y12 inhibitor use are independent predictors of high on-aspirin platelet reactivity in elderly CAD patients.
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SUA modestly linked to HAPR on aspirin; hypothesis-generating and should not yet change practice.
Zhang et al. (2017) conducted an observational in Coronary artery disease (n=275). Risk factors (serum uric acid, platelet count, hematocrit, P2Y12 inhibitors) was evaluated on High on-aspirin platelet reactivity (HAPR) (OR 1.004, 95% CI 1.000-1.007, p=0.048). Serum uric acid (OR 1.004), platelet count, hematocrit, and concomitant P2Y12 receptor inhibitor use (OR 1.965) were independently correlated with high on-aspirin platelet reactivity.
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