Key result
Central venous pressure correlated significantly with pulmonary wedge pressure only in patients without a prior history of cardiopulmonary disease (P<0.01), but not in those with such history (P>0.50).
Why the study?
Does central venous pressure (CVP) reliably correlate with pulmonary wedge pressure (PWP) in critically ill surgical patients?
Observational (n=27)
Does central venous pressure (CVP) reliably correlate with pulmonary wedge pressure (PWP) in critically ill surgical patients?
p-value: p=<.01
Central venous pressure is a reliable guide to cardiac performance only in patients without pre-existing cardiopulmonary disease, as normal CVP may mask left ventricular failure in those with prior disease.
CVP may mislead left-heart assessment in surgical patients with cardiopulmonary disease history; Level 4 data leaves open need for prospective outcome trials.
To assess the reliability of the central venous pressure (CVP) as an adequate guide to cardiac performance, we inserted a balloon-tipped pulmonary artery catheter (Swan-Ganz 7F, 110 cm) in 27 critically ill surgical patients, and simultaneously measured CVP and pulmonary wedge pressure (PWP). Thirteen patients with a previous history of cardiopulmonary disease showed a poor correlation between CVP and PWP (P>.50). Fourteen patients with no prior history of cardiopulmonary disease showed a significant correlation between CVP and PWP (P<.01). Our findings suggest that the CVP provides a reliable assessment of cardiac function only in the absence of cardiopulmonary disease. Left ventricular failure and pulmonary congestion may be present in these patients even though CVP is normal.
No takes yet. Share an insight, caveat, or question.
George P.MacLaren Toussaint (1974) conducted an observational in Critically ill surgical illness (n=27). Central venous pressure (CVP) vs. Pulmonary wedge pressure (PWP) was evaluated on Correlation between CVP and PWP (p=<.01). Central venous pressure correlated significantly with pulmonary wedge pressure only in patients without a prior history of cardiopulmonary disease (P<0.01), but not in those with such history (P>0.50).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: