An analysis of pump thrombus events in patients in the HeartWare ADVANCE bridge to transplant and continued access protocol trial
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Discussion
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Implication
Randomized trial analyzes pump thrombus incidence and treatment effectiveness in LVAD patients, suggesting management improvements.
Key Points
- This study aims to analyze the incidence of pump thrombus events and identify risk factors in patients receiving the HVAD.
- Included 382 patients implanted with HVAD as part of the HeartWare Bridge to Transplant and Continued Access Protocol trial.
- Conducted multivariate analysis to assess risk factors for pump thrombus development.
- Used descriptive statistics for analyzing baseline characteristics and treatment outcomes.
- Observed 34 pump thrombus events in 31 patients, an incidence of 8.1%.
- Success rate of medical management was 50% in attempted cases; 15 of 30 cases successfully managed.
- 1-year survival rates were 69.4% for patients with pump thrombus and 85.5% for those without (p = 0.21).
Cite This Study
Najjar et al. (2013) studied this question.