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June 28, 2026˜The œmedical letter on drugs and therapeutics/˜The œmedical letter

Fosfomycin (Contepo) for Complicated Urinary Tract Infections

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Overview

Randomized trial shows effectiveness of IV fosfomycin in adults with complicated UTIs, indicating a new treatment option.

Key Points

  • The aim is to evaluate the efficacy of IV fosfomycin for complicated urinary tract infections caused by specific bacteria.
  • FDA approval of IV fosfomycin for adults with cUTIs caused by susceptible Escherichia coli or Klebsiella pneumoniae.
  • Comparative analysis with oral formulation, which is used for uncomplicated UTIs.
  • IV fosfomycin is now approved as a treatment option for cUTIs.
  • Oral fosfomycin has been a long-standing option for uncomplicated cases.

Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a40b8ed61bb0a67205c56echttps://doi.org/10.58347/tml.2026.1758b
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