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June 28, 2026Clinical Otolaryngology

Oxymetazoline Can Shorten the Time Required for a Bronchoscope to Reach the Vocal Cords in Patients With Turbinate Hypertrophy

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Authors

JZJie ZhangFMFanliang Meng

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Overview

Randomized trial examines oxymetazoline's effects on bronchoscopy time in turbinate hypertrophy patients, suggesting enhanced outcomes.

Key Points

  • To investigate how oxymetazoline affects bronchoscope navigation time, nasal manipulation, mucosal injury, and pain in patients with turbinate hypertrophy.
  • Prospective, double-blinded, randomized controlled trial
  • Enrolled 240 patients with turbinate hypertrophy, grouped into oxymetazoline, saline, and control groups (n=80 each)
  • Evaluated outcomes included bronchoscope-to-vocal-cords time and various pain and trauma scales.
  • Oxymetazoline group had a bronchoscope-to-vocal-cords time of 44.00 s vs. 52.00 s for saline (p<0.001)
  • Improved nasal passage ease with negotiation VAS 3.00 vs. 5.00 for saline (p<0.001)
  • Reduced mucosal trauma (Trauma VAS 7.00 vs. 9.00, p<0.001) and lower nasal pain scores for oxymetazoline patients.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a40b9f361bb0a67205c6017https://doi.org/10.1111/coa.70118
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