What question did this study set out to answer?

This research aims to evaluate the prevalence of oral disorders and differences in dental health among patients with primary Sjögren disease compared to controls.

June 28, 2026Journal of Dental Research

Oral Burden of Sjögren Disease: A Systematic Review and Meta-analysis

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Authors

AHA. HeizerSemmelweis University MKM. KisgergelySemmelweis University BSB. SzabóSemmelweis University

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Implication

Systematic review assesses oral disorders in primary Sjögren disease, indicating high risk and need for dental care.

Key Points

This research aims to evaluate the prevalence of oral disorders and differences in dental health among patients with primary Sjögren disease compared to controls.
Performed a systematic search across PubMed, EMBASE, and CENTRAL.
Included 75 studies, with 49 eligible for meta-analysis, focusing on adult patients with primary Sjögren disease.
Calculated pooled outcomes using random-effects models for odds ratio and mean difference of dental indices.
Patients with primary Sjögren disease have a 10.5 times increased risk for candidiasis (OR: 10.5; CI: 6.99 to 15.79).
Higher risk for dysphagia (OR: 26.78; CI: 20.94 to 34.25) and dysgeusia (OR: 17; CI: 4.52 to 63.96).
Patients show significant differences in dental health with fewer teeth (MD: -2.16; CI: -4.27 to -0.05) and higher decay scores (MD: 20.45; CI: 10.16 to 30.74).

Cite This Study

Heizer et al. (2026) studied this question.

synapsesocial.com/papers/6a40bae361bb0a67205c6a3c https://doi.org/10.1177/00220345261450057

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Oral Burden of Sjögren Disease: A Systematic Review and Meta-analysis

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Oral Burden of Sjögren Disease: A Systematic Review and Meta-analysis

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Cite This Study

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