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October 5, 2017Future Science OAOpen Access

Liver Fibrosis: A Compilation on the Biomarkers Status and Their Significance During Disease Progression

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Authors

KNKrishna Sumanth NallagangulaSNShashidhar Kurpad NagarajVLV Lakshmaiah

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Overview

Review highlights the impact of biomarkers on liver fibrosis diagnosis, indicating their critical role in managing chronic liver injury.

Key Points

  • This review aims to evaluate the diagnostic accuracy of biomarkers and scoring systems for liver fibrosis.
  • Compilation of various biomarkers, both direct and indirect, for liver fibrosis assessment.
  • Discussion of mathematical equations combining biomarker tests to improve diagnostic outcomes.
  • Review of advancements in -omics approaches for identifying potential biomarker candidates.
  • Biomarkers offer clinically significant insights into liver fibrosis, but single markers alone may not suffice.
  • Combination of tests through mathematical equations enhances the accuracy of liver fibrosis diagnosis.
  • The need for further evaluation of -omics derived biomarker candidates is emphasized.

Cite This Study

Nallagangula et al. (2017) studied this question.

synapsesocial.com/papers/6a4166eab7b89a99a2fe2dfehttps://doi.org/10.4155/fsoa-2017-0083
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