Key result
Reactive oxygen species generated by platelets participate in intracellular signaling to regulate platelet activation and thrombus formation.
Design
Review
Authors
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ROS inhibition may offer a novel antiplatelet approach; leaves open its net clinical benefit pending targeted trials.
This review highlights the role of platelet-generated reactive oxygen species in regulating platelet activation and thrombus formation, suggesting potential therapeutic targets.
Krötz et al. (2004) conducted a review in Platelet activation. Reactive oxygen species was evaluated. Reactive oxygen species generated by platelets participate in intracellular signaling to regulate platelet activation and thrombus formation.
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