Key result
Combined preeclampsia and IUGR in pregnancy correlates with worse GLS than either condition alone.
Why the study?
Preeclampsia and foetal growth restriction are linked to later maternal cardiovascular disease, but subclinical cardiac abnormalities are discernible beforehand using speckle-tracking echocardiography strain measurement.
Does 2D speckle-tracking echocardiography detect subclinical cardiac dysfunction in pregnant women with preeclampsia and/or IUGR?
Cross-Sectional (n=75)
No
Does 2D speckle-tracking echocardiography detect subclinical cardiac dysfunction in pregnant women with preeclampsia and/or IUGR?
GLS assessment by 2D speckle-tracking echocardiography can detect early subclinical left ventricular dysfunction in pregnant women with preeclampsia and IUGR despite normal ejection fraction.
Preeclampsia may indicate subclinical LV dysfunction via reduced GLS; leaves open need for longitudinal studies before clinical adoption.
A higher chance of maternal cardiovascular disease in later life is linked to pregnancies complicated by preeclampsia and foetal growth restriction. Before significant cardiovascular illness manifests itself, subclinical cardiac abnormalities are discernible. An elegant way to evaluate subclinical cardiac dysfunction is to use strain measurement in conjunction with speckle-tracking echocardiography (STE). The current study sought to assess the subclinical cardiac dysfunction in mothers with pree
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Saadati et al. (2024) conducted a cross-sectional in Preeclampsia and Intrauterine Growth Restriction (IUGR) (n=75). Preeclampsia and/or IUGR vs. Between-group comparison was evaluated on Mean Global Longitudinal Strain (GLS) (p=0.001). Pregnant women with both preeclampsia and intrauterine growth restriction had significantly lower mean global longitudinal strain (-18.56%) compared to those with preeclampsia (-19.97%) or IUGR (-20.59%).
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