Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 6, 2019Journal of Cardiovascular and Thoracic ResearchOpen Access

Comparison of left ventricular systolic function by 2D speckle-tracking echocardiography between normal pregnant women and pregnant women with preeclampsia

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Previous studies reported significant effects of preeclampsia on cardiac dimensions, prompting evaluation of LV systolic and diastolic functions and cardiac strain in patients with preeclampsia.

Does preeclampsia alter left ventricular systolic function and cardiac strain compared to normal pregnancy?

Population

Healthy pregnant women and pregnant women suffering from preeclampsia

Comparison

Pregnant women with preeclampsia vs healthy pregnant women

Design

Cross-sectional study

Authors

AMAtoosa MostafaviYZYaser Tase ZarFNFarahnaz Nikdoust

Discussion

Loading...

Member takes

Overview

Preeclampsia is associated with subclinical left ventricular systolic dysfunction, as evidenced by reduced global circumferential strain and increased ventricular dimensions.

Key Points

  • To assess alterations in left ventricular systolic and diastolic dimensions and strain mechanics in pregnant women with preeclampsia compared to healthy pregnant controls.
  • Cross-sectional single-center study comparing healthy pregnant women to pregnant women diagnosed with preeclampsia who presented for routine healthcare.
  • Left ventricular strain and chamber dimensions were evaluated using 2D speckle-tracking echocardiography.
  • Women with preeclampsia had significantly increased left ventricular end-diastolic diameter (47.43 ± 4.94 mm vs 44.84 ± 4.30 mm; P = 0.008), left ventricular end-systolic diameter (31.16 ± 33.3 mm vs 29.20 ± 3.75 mm; P = 0.008), and right ventricular diameter (27.93 ± 1.71 mm vs 24.53 ± 23.3 mm; P = 0.001).
  • Global circumferential strain was significantly lower in the preeclampsia group compared to healthy controls (-20.4 ± 12.4 vs -22.68 ± 5.50; P = 0.028).
  • Global longitudinal strain did not differ significantly between the preeclampsia group and healthy controls (-18.69 ± 2.8 vs -19.39 ± 3.49; P = 0.164).

Structured PICO

Does preeclampsia alter left ventricular systolic function and cardiac strain compared to normal pregnancy?

P
Population
Pregnant women with preeclampsia and healthy pregnant women referred for routine healthcare services
I
Intervention
Preeclampsia (observational exposure)
C
Comparator
Healthy pregnant women
O
Outcome
Left ventricular systolic and diastolic functions, including cardiac strain measured by 2D speckle-tracking echocardiographysurrogate

Preeclampsia is associated with subclinical left ventricular systolic dysfunction, as evidenced by reduced global circumferential strain and increased ventricular dimensions.

Cite This Study

Mostafavi et al. (2019) studied this question.

synapsesocial.com/papers/6a7e7c76f6941e90164c4e81https://doi.org/10.15171/jcvtr.2019.50
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural and functional changes in left ventricle during normotensive and preeclamptic pregnancy2002 · 296 citations
  2. 2Acute Cardiac Effects of Severe Pre-Eclampsia2018 · 173 citations
  3. 3Left ventricular function of patients with pregnancy‐induced hypertension evaluated using velocity vector imaging echocardiography and N‐terminal pro‐brain natriuretic peptide2018 · 37 citations
  4. 4Left Ventricular Function in Gestational Hypertension: Serial Echocardiographic Study2009 · 26 citations
  5. 5Electrocardiographic findings in women with a recent history of pre‐eclampsia2011 · 9 citations