Why the study?
Does preeclampsia impair maternal left ventricular and endothelial functions compared to normal pregnancy?
Population
40 pregnant women
Comparison
Preeclampsia vs Normal pregnancy
Design
Cohort
Follow-up
three months after delivery
Key result
Preeclampsia was associated with impaired maternal left ventricular function during pregnancy that normalized postpartum, and persistently impaired endothelial function at three months after delivery.
Authors
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Persistent endothelial dysfunction after preeclampsia may warrant postpartum monitoring; leaves open its link to long-term cardiovascular outcomes.
Observational (n=40)
Yes
Does preeclampsia impair maternal left ventricular and endothelial functions compared to normal pregnancy?
Preeclampsia is associated with transient left ventricular dysfunction during pregnancy and persistent endothelial dysfunction up to three months postpartum.
Tyldum et al. (2011) conducted an observational in Preeclampsia (n=40). Preeclampsia vs. Normal pregnancy was evaluated on Early diastolic mitral annular tissue velocity ('e'), peak systolic tissue velocity ('S'), and flow-mediated dilation. Preeclampsia was associated with impaired maternal left ventricular function during pregnancy that normalized postpartum, and persistently impaired endothelial function at three months after delivery.
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