Why the study?
There is a relative lack of knowledge regarding cardiac functional and structural changes in preeclampsia, which may lead to iatrogenic adverse consequences during management.
Does preeclampsia alter maternal cardiac structural and functional echocardiographic indices compared to healthy pregnancy?
Population
30 women with preeclampsia and 30 gestationally-matched healthy pregnant controls
Comparison
Pregnant women with preeclampsia vs healthy pregnant controls
Design
Cross-sectional study
Key result
Preeclampsia was associated with a 36.7% rate of diastolic dysfunction and a 43.3% rate of left ventricular hypertrophy, compared to 0% for both in healthy pregnant women.
Authors
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May support echocardiographic monitoring in preeclampsia; leaves open whether changes predict long-term cardiovascular risk.
Cross-Sectional (n=60)
Yes
Does preeclampsia alter maternal cardiac structural and functional echocardiographic indices compared to healthy pregnancy?
Absolute Event Rate: 36.7% vs 0%
Preeclampsia is associated with significant left ventricular diastolic dysfunction and hypertrophy while preserving systolic function, indicating adaptive structural remodeling to increased afterload.
Parveen et al. (2023) conducted a cross-sectional in Preeclampsia (n=60). Preeclampsia vs. Healthy pregnant women was evaluated on Diastolic dysfunction. Preeclampsia was associated with a 36.7% rate of diastolic dysfunction and a 43.3% rate of left ventricular hypertrophy, compared to 0% for both in healthy pregnant women.
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