Why the study?
The study was conducted to determine the risk of 30-day hospital readmission associated with medical conditions and drug regimens in polymedicated older inpatients discharged home.
Are specific medical conditions and drug regimens associated with an increased risk of 30-day hospital readmission in polymedicated older adults discharged home?
Population
8878 polymedicated, home-dwelling patients over 64 years old across 20 422 inpatient stays
Comparison
Medical conditions and drug regimens associated with readmission
Design
Registry-based cohort study
Follow-up
30 days
Key result
Among polymedicated older adults discharged home, the 30-day readmission rate was 7.8%, with risk significantly increased by polypharmacy (OR 1.043 per additional drug; 95% CI 1.028-1.058).
Authors
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Longer LOS modestly associated with higher readmission; leaves open whether shortening stay improves outcomes.
Cohort (n=8,878)
No
Are specific medical conditions and drug regimens associated with an increased risk of 30-day hospital readmission in polymedicated older adults discharged home?
Odds Ratio: 1.043 (95% CI 1.028–1.058)
In polymedicated older adults discharged home, polypharmacy and specific drug classes, including antihypertensives, are associated with an increased risk of 30-day hospital readmission.
Pereira et al. (2021) conducted a cohort in Polymedicated, older inpatients discharged home (n=8,878). Polypharmacy and specific medical conditions vs. Fewer prescribed drugs or absence of specific conditions was evaluated on 30-day hospital readmission (OR 1.043, 95% CI 1.028-1.058). Among polymedicated older adults discharged home, the 30-day readmission rate was 7.8%, with risk significantly increased by polypharmacy (OR 1.043 per additional drug; 95% CI 1.028-1.058).