Stress CMR is a cost-effective, non-invasive test that accurately assesses myocardial ischemia, myocardial viability, and cardiac function without the need for ionizing radiation. There is a large body of literature, including randomized-controlled trials, validating its diagnostic performance, risk stratification capabilities, and ability to guide appropriate use of coronary intervention. Specifically, stress CMR has demonstrated higher diagnostic sensitivity than SPECT in detecting angiographically significant coronary artery disease. Stress CMR is particularly valuable for the evaluation of patients with moderate to high pre-test probability of having stable ischemic heart disease and for patients known to have challenging imaging characteristics such as women, individuals with prior revascularization, and left ventricular dysfunction. In this article, we review the basics principles of stress CMR, the data supporting its clinical use, the added-value of myocardial blood flow quantification, and the assessment of myocardial function and viability routinely obtained during a stress CMR study.
Patel et al. (Fri,) studied this question.