Dermatophytosis, a fungal infection of the skin, is a widespread public health concern. The increasing resistance to antifungal drugs and the side effects associated with conventional chemical treatments highlight the need for new, plant-based therapeutic options. Tulsi (Ocimum sanctum), a well-known medicinal herb, has shown significant antifungal properties mainly due to its essential oil components such as eugenol and linalool. However, developing a stable, effective, and user-friendly topical delivery system for Tulsi extract remains a challenge. Gel-based formulations are considered a promising approach, as they are non-greasy, easy to apply, provide a cooling effect and allow controlled drug release. The present study aims to compile and critically analyse the existing literature on the formulation and evaluation of antifungal herbal gels containing Tulsi. The gel formulation was prepared using a standardised method. It was then evaluated for its in vitro antifungal activity against common fungal pathogens. In addition, key physicochemical properties such as pH, viscosity, spreadability, and drug content were assessed.
Kadam et al. (Sat,) studied this question.