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Randomized trial reports corrected data on safety outcomes in atopic dermatitis, indicating importance of accurate reporting.
Bunick CG, Irvine AD, Silverberg JI, et al. Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years. J Eur Acad Dermatol Venereol. 2026;40(5):856-866. doi:https://doi.org/10.1111/jdv.70172. On Page 5, the sentence that reads ‘There were two fatal VTE events across all studies, both a result of pulmonary embolism (Table 3)’ is incorrect. The sentence should read: ‘A total of 11 cases of venous thromboembolic events were reported; six of these were SAEs and none were fatal’. There is also an error in Table 3 in the second row of the ‘~1 year’ column. The data for the ~1-year columns for ‘Any AE leading to discontinuation of study drug’ should read 4.4 [3.3, 5.6] for UPA 15 mg (in place of 95.2 [90.1, 100.5]) and 5.7 [4.5, 7.1] for UPA 30 mg (in place of 117.6 [112.0, 123.4]). The revised Table 3 is provided below We apologize for these errors.
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A 2026 study studied this question.
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