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Investigate the rare presentation of colonic lymphoma as fecal peritonitis and its management.

June 29, 2026CureusOpen Access

Colonic Diffuse Large B-Cell Lymphoma Presenting as Fecal Peritonitis: A Case Report

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Case report reveals diffuse large B-cell lymphoma causing fecal peritonitis, suggesting critical surgical intervention.

Investigate the rare presentation of colonic lymphoma as fecal peritonitis and its management.
Emergency right oncologic colectomy performed due to cecal tumor perforation and fecal peritonitis.
Histopathological examination confirmed diffuse large B-cell lymphoma, germinal center type.
Patient received four cycles of R-CHOP immunochemotherapy after surgery.
Histopathology confirmed 90% Ki-67 proliferation index and CD79a-positive, CD3-negative tumor characteristics.
PET-CT evaluation at six months showed partial response to ongoing treatment.
Patient's postoperative recovery was uneventful after a brief ICU stay.

Ouryemchi et al. (2026) studied this question.

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