Key result
Visceral, epicardial, and intermuscular adipose tissue depots correlate with increased cardiovascular and metabolic risk, whereas subcutaneous fat is associated with favorable lipid profiles.
Population
Human studies related to the differential characteristics of various white adipose tissue (WAT) depots
Design
Review
Authors
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May inform nuanced CV risk assessment beyond BMI; leaves open causal effects and targeted therapies for ectopic fat.
Different white adipose tissue depots have distinct structural and functional properties, with visceral and ectopic fat depots correlating with increased cardiovascular and metabolic risk.
Wrońska et al. (2012) conducted a review in Adipose tissue distribution. White adipose tissue depots (visceral, subcutaneous, epicardial, intermuscular) was evaluated. Visceral, epicardial, and intermuscular adipose tissue depots correlate with increased cardiovascular and metabolic risk, whereas subcutaneous fat is associated with favorable lipid profiles.
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