Key result
Increased use of drug-eluting stents over 5 years was associated with a reduction in in-hospital major adverse cardiac events from 3.1% in 2004-2005 to 1.0% in 2008-2009 (P<0.001).
Why the study?
Does the increasing use of drug-eluting stents (DES) over time improve in-hospital outcomes in patients undergoing PCI?
Population
21,667 patients who underwent percutaneous coronary intervention at Fu Wai Hospital over a 5-year period
Comparison
Percutaneous coronary intervention with… vs Earlier time periods with lower DES use
Design
Cohort
Follow-up
in-hospital
Authors
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Supports temporal gains in PCI safety at one high-volume center; leaves open whether DES or other factors drove improvements in this observational registry.
Cohort (n=21,667)
No
Does the increasing use of drug-eluting stents (DES) over time improve in-hospital outcomes in patients undergoing PCI?
Absolute Event Rate: 1% vs 3.1%
p-value: p=<0.001
The increasing use of drug-eluting stents over a 5-year period was associated with significant reductions in in-hospital major adverse cardiac events and target-vessel revascularization.
Liu et al. (2010) conducted a cohort in Percutaneous coronary intervention (PCI) (n=21,667). Drug-eluting stents (DES) use over time vs. Earlier time periods (2004-2005) was evaluated on In-hospital major adverse cardiac events (p=<0.001). Increased use of drug-eluting stents over 5 years was associated with a reduction in in-hospital major adverse cardiac events from 3.1% in 2004-2005 to 1.0% in 2008-2009 (P<0.001).
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