Key result
Examination of a degenerated mitral surgical bioprosthesis and subsequent TMVR revealed massive calcification and fibrous tissue overgrowth at 4 years follow-up.
Why the study?
TMVR is indicated for degenerated bioprostheses in high-risk patients, but durability of these valves remains an important issue.
Case Report (n=1)
Highlights the risk of early structural valve deterioration and massive calcification in both surgical and transcatheter valve-in-valve mitral bioprostheses at 4 years, emphasizing the need for strict follow-up.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to potential early mitral bioprosthetic failure; leaves open durability questions for TMVR after surgical valve degeneration.
INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high-risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesis and of a subsequent bovine TMVR, both at 4 years follow-up, is here presented. RESULTS: Gross, histopathologic, and X-ray examination revealed massive calcification of both devices and fibrous tissue overgrowth involving the TMVR stent. CONCLUSIONS: Careful clinical evaluation and strict follow-up are mandatory to identify early signs of dysfunction and to intervene in a timely manner.
No takes yet. Share an insight, caveat, or question.
Tessari et al. (2021) conducted a case report in Degenerated mitral bioprosthesis (n=1). Transcatheter mitral valve replacement (TMVR) valve-in-valve was evaluated on Structural valve deterioration. Examination of a degenerated mitral surgical bioprosthesis and subsequent TMVR revealed massive calcification and fibrous tissue overgrowth at 4 years follow-up.
Synapse has enriched 10 related papers. Consider them for comparative context: