Key result
Transcatheter mitral valve replacement for postsurgical failures reduced mean mitral gradient (9.5 to 5.5 mm Hg, P<0.01), though thrombotic-related dysfunction occurred in 15% of patients.
Why the study?
Does transcatheter mitral valve replacement (TMVR) provide procedural success and acceptable safety in patients with degenerated surgical mitral valve repair or prostheses?
Observational (n=13)
Does transcatheter mitral valve replacement (TMVR) provide procedural success and acceptable safety in patients with degenerated surgical mitral valve repair or prostheses?
TMVR for degenerated surgical mitral valves is technically feasible and reduces mitral gradients, but is associated with a notable risk of valve thrombosis, suggesting a potential need for routine oral anticoagulation post-procedure.
No takes yet. Share an insight, caveat, or question.
Small retrospective TMVR series supports procedural feasibility; leaves open durability, safety, and selection criteria for prospective study.
Eng et al. (2017) conducted an observational in Degenerated surgical mitral valve repairs or surgical prostheses (n=13). Transcatheter mitral valve replacement (TMVR) was evaluated on Immediate procedural MVARC defined technical success. Transcatheter mitral valve replacement for postsurgical failures reduced mean mitral gradient (9.5 to 5.5 mm Hg, P<0.01), though thrombotic-related dysfunction occurred in 15% of patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: