Key result
The PRECISE-DAPT score was a more accurate predictor of contrast-induced nephropathy than the Mehran score in acute coronary syndrome patients undergoing PCI (AUC difference 0.183, p=0.005).
Why the study?
The study was conducted to evaluate the predictive value of the PRECISE DAPT score for the development of CIN in acute coronary syndrome patients undergoing PCI and compare it with the Mehran score.
Does the PRECISE-DAPT score predict contrast-induced nephropathy better than the Mehran score in acute coronary syndrome patients undergoing PCI?
Observational (n=100)
Does the PRECISE-DAPT score predict contrast-induced nephropathy better than the Mehran score in acute coronary syndrome patients undergoing PCI?
The PRECISE-DAPT score may serve as a more accurate and easily determined tool for predicting contrast-induced nephropathy compared to the Mehran score in ACS patients undergoing primary PCI.
Supports PRECISE-DAPT for CIN stratification in small cohorts; hypothesis-generating and requires validation before practice change.
Background: Contrast-induced nephropathy (CIN) is defined as the absolute ≥ 0.5 mg/dL or relative > 25% increase in serum creatinine from baseline on admission to 48–72 h following exposure to intravascular iodinated contrast media. Aim and objectives: to assess the predictive value of The PRECISE DAPT score for the development of CIN in acute coronary syndrome cases undergoing PCI and compare its predictive power to the Mehran score. Subjects and methods: This Prospective observational research was included 100 cases had Acute coronary syndrome and performed PCI. Cases were classified into group 1 (13 cases had CIN) and group 2 (87 cases had no CIN). Cases were subjected to standard 12-leads ECG, primary PCI and calculation of PRECISE-DAPT, Mehran score scores. Results: PRECISE-DAPT score is a more accurate predictor of CIN than Mehran score (difference between both AUCs 0.183, p =0.005). There was insignificantly different in PCI interventional data and complications between two groups. Conclusions: The PRECISE- DAPT score could be determined easily. This scoring system is effective for estimating CIN at early stage and determining therapy measures. Follow-up of cases had higher PRECISEDAPT score done more carefully and mentioned that these cases have an increased risk of CIN.
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ELhashash et al. (2023) conducted an observational in Acute coronary syndrome (n=100). PRECISE-DAPT score vs. Mehran score was evaluated on Contrast-induced nephropathy (CIN) (AUC difference 0.183, p=0.005). The PRECISE-DAPT score was a more accurate predictor of contrast-induced nephropathy than the Mehran score in acute coronary syndrome patients undergoing PCI (AUC difference 0.183, p=0.005).
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