Key result
Off-hours primary PCI for STEMI shows no difference in 1-year mortality versus on-hours admission.
Why the study?
Treatment delay affects STEMI outcomes, but the effect of admission time is unknown when PCI is the preferred reperfusion strategy.
Does off-hours admission compared to on-hours admission affect reperfusion delays or mortality in STEMI patients treated with primary PCI?
Cohort (n=1,222)
No
Does off-hours admission compared to on-hours admission affect reperfusion delays or mortality in STEMI patients treated with primary PCI?
Hazard Ratio: 1.1 (95% CI 0.74–1.64)
Absolute Event Rate: 10% vs 10%
p-value: p=0.64
In a contemporary emergency network, off-hours admission for STEMI does not adversely affect reperfusion times or mortality compared to on-hours admission.
Introduction and objectives: In patients with ST-segment elevation myocardial infarction (STEMI) treatment delay significantly affects outcomes. The effect of admission time in STEMI patients is unknown when percutaneous coronary intervention (PCI) is the preferred reperfusion strategy. This study aimed to determine the association between STEMI outcomes and the timing of admission in a PCI center in south-western Europe. Methods: This retrospective cohort study analyzed the local electronic data from 1222 consecutive STEMI patients treated with PCI. On-hours were defined as admission from Monday to Friday between 8:00 AM and 6:00 PM on non-national holidays. Results: = .64). Conclusions: In a contemporary emergency network, the timing of STEMI patients' admission to the PCI center was not associated with reperfusion delays or increased mortality.
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Mané et al. (2024) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=1,222). On-hours admission vs. Off-hours admission was evaluated on 1-year mortality (HR 1.1, 95% CI 0.74-1.64, p=0.64). On-hours admission for primary percutaneous coronary intervention in patients with STEMI was not associated with a difference in 1-year mortality compared to off-hours admission (HR 1.1).
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