Key result
Macrophage polarization is a dynamic, non-fixed process in which macrophages integrate multiple environmental signals from microbes and damaged tissues.
Design
Review
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No immediate change to cardiac therapies; leaves open whether dynamic polarization can be targeted to modulate myocyte function.
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...
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G. A. Langer (1973) studied this question. Macrophage polarization is a dynamic, non-fixed process in which macrophages integrate multiple environmental signals from microbes and damaged tissues.
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