Key result
Incident hemodialysis patients had significantly higher global native T1 times on cardiac MRI compared to healthy volunteers (1171 ± 27 ms vs. 1154 ± 32 ms), consistent with myocardial fibrosis.
Why the study?
Does native T1 mapping on cardiac MRI detect myocardial tissue abnormalities consistent with fibrosis in incident hemodialysis patients compared to healthy volunteers?
Cross-Sectional (n=61)
Does native T1 mapping on cardiac MRI detect myocardial tissue abnormalities consistent with fibrosis in incident hemodialysis patients compared to healthy volunteers?
Native T1 mapping on cardiac MRI can noninvasively detect myocardial tissue abnormalities consistent with fibrosis in hemodialysis patients, offering a safe alternative to contraindicated gadolinium contrast.
Answers are grounded in this paper and cite their sources.
Native T1 mapping may detect myocardial fibrosis in hemodialysis; leaves open prognostic value and therapeutic implications.
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Rutherford et al. (2016) conducted a cross-sectional in End-stage renal disease (n=61). End-stage renal disease (hemodialysis) vs. Healthy volunteers was evaluated on Global native T1 relaxation time. Incident hemodialysis patients had significantly higher global native T1 times on cardiac MRI compared to healthy volunteers (1171 ± 27 ms vs. 1154 ± 32 ms), consistent with myocardial fibrosis.
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