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This study evaluates ketamine use for procedural sedation and analgesia in pediatric emergency care, focusing on adverse events.

Pediatric Procedural Sedation and Analgesia with Ketamine and Adverse Events in the Emergency Department

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This study evaluates ketamine use for procedural sedation and analgesia in pediatric emergency care, focusing on adverse events.
Prospective observational study of pediatric patients aged 3 months to 18 years undergoing ketamine-based sedation in the emergency department.
Data collected included demographics, ketamine dosing, vital signs, sedation levels, and adverse events.
Adverse events were recorded pre-, intra-, and post-procedure.
Sixty pediatric patients were included, mostly ASA I (98.3%).
Adverse events included agitation (16.7%), hiccups (11.7%), and muscle twitching (10%) with no severe complications.
Significant increases in systolic and diastolic blood pressure were observed, but no serious adverse events occurred.

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Prospective observational study assesses adverse events of ketamine-based sedation in pediatric patients, suggesting a favorable safety profile.

Balci et al. (2026) studied this question.

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Prospective observational study assesses adverse events of ketamine-based sedation in pediatric patients, suggesting a favorable safety profile.